Single-use aseptic sampling assemblies
Preassembled fluid paths for closed, representative sample collection from bioreactors, mixers, vessels and process-transfer lines.
Final suitability depends on the process interface, sample method, assay and approved assembly configuration
Product overview
Sampling systems combine a process connection, controlled fluid path and one or more collection containers in a preassembled single-use assembly. The configuration is selected around the sample plan, assay and host equipment.
Sanitary, aseptic, weldable-tubing or valve-based connections can link the sampling assembly to a compatible bioreactor, mixer, vessel or transfer line.
Integration point Vessel or transfer line
Bags, bottles, tubes or syringes may be integrated according to the required sample volume, analytical method, transport conditions and laboratory handling workflow.
Container formats Bag, bottle, tube or syringe
Sampling strategy and configuration selection
Selection should consider sample frequency, required volume, representative draw strategy, flush or hold-up allowance, container format, disconnection method and the analytical workflow.
End-user applications
Configurable assemblies support routine process monitoring, in-process testing and sample transfer while maintaining the intended process boundary.
Samples for cell density, metabolites, nutrients, pH, osmolality and other process measurements.
Planned sampling from compatible microbial-culture and fermentation equipment.
Sample collection during preparation, hold, storage and distribution operations.
In-process sampling across clarification, purification and intermediate hold steps.
Sampling of formulated bulk fluid and compatible filling-process transfer paths.
Collection for bioburden, endotoxin, sterility-related or other defined quality tests.
Quotation preparation
Confirm the host equipment, collection sequence, container format, tubing, disconnection and packaging requirements before technical review.
Identify the vessel or line, connection type, mating interface and installation method.
State sample volume, number of samples, frequency, flush allowance and permitted residual volume.
Select bags, bottles, tubes or syringes and define material, capacity, closure and labeling.
Specify tubing material, line size, length, flow control and separation method.
Define irradiation, protective packaging, leak testing, identification and documentation expectations.
Configuration matrix
Available materials, connectors, containers, sterilization and packaging depend on the approved assembly. Sample-container and tubing compatibility should be confirmed for the intended fluid and analytical method.
| Configuration area | Available choices | Selection purpose |
|---|---|---|
| Sampling architecture | Direct single-sample assembly, multi-container manifold or sequential sample train | Match the number, order and frequency of required sampling events |
| Collection container | Flexible sample bag, bottle, tube or syringe; material and capacity configurable | Match sample volume, assay, transport and laboratory handling |
| Process connection | Sanitary clamp, aseptic connector, weldable tubing, luer or compatible sampling valve | Integrate the assembly with the vessel, mixer, bioreactor or transfer line |
| Tubing | Platinum-cured silicone or weldable thermoplastic elastomer; line size and length configurable | Support connection, flow, welding or sealing requirements |
| Flow control and disconnection | Clamps, valves, pinch-and-separate components, weld or seal-and-cut strategy by approved configuration | Control filling and separate each sample while protecting the intended process boundary |
| Identification | Customer-defined labels, sample position identification and traceability options | Support sample sequencing, handling and laboratory transfer |
| Packaging and preparation | Single or double protective packaging; gamma-irradiated and leak-tested options by approved configuration | Align the assembly with installation, handling and quality requirements |
Confirm the process interface, sample volume and frequency, collection containers, tubing, flow control, disconnection, irradiation and packaging requirements before technical review.