Single-use rocking bioreactor assemblies
Low-shear cultivation bags that use platform rocking to create waves for circulation and gas transfer.
Sensor performance, retention area and permitted rocking settings require confirmation with the selected platform and process
Product overview
Rocking bioreactor bags support seed expansion, development and intensified small-scale processing in a closed culture chamber. Supplied interfaces are selected according to the required control level.
Platform rocking creates a moving liquid surface that supports mixing and gas exchange without an internal rotating impeller.
Mixing approach Platform-generated waves
Air filters, feed and harvest lines, sampling and process interfaces are supplied according to the selected configuration.
Configuration range Basic through perfusion-ready
Configuration and process selection
Choose basic, sensor-ready or perfusion-ready operation according to the required monitoring, process lines and retention functions.
End-user applications
The portfolio supports routine expansion, process development and perfusion-ready workflows where rocking operation is supported by the process.
Seed-train expansion and inoculum preparation.
Suspension cell culture in batch or fed-batch mode.
Adherent or microcarrier culture where process development supports rocking operation.
Process development, media screening and scale-down work.
N-1 intensification and perfusion culture.
Low-shear cultivation of sensitive cells.
Quotation preparation
Confirm the operating range, selected control level, gas and exhaust requirements, liquid lines and sensor compatibility before technical review.
State platform tray size, minimum and maximum working volumes and expected expansion ratio.
Select basic, sensor-ready or perfusion-ready operation.
Define inlet gas, exhaust-filter and check-valve requirements.
Specify inoculation, feeds, sampling, harvest, drain and perfusion lines.
Confirm optical pH/DO compatibility and the intended controller.
Technical specification matrix
Optical sensor performance, retention-area requirement and permitted rocking settings must be confirmed with the selected platform and process.
| Nominal bag size | Minimum working volume | Maximum working volume | Optional retention membrane |
|---|---|---|---|
| 2 L | 0.2 L | 1 L | 160 × 160 mm |
| 10 L | 1 L | 5 L | 160 × 160 mm |
| 20 L | 2 L | 10 L | 350 × 350 mm |
| 50 L | 5 L | 25 L | 350 × 350 mm |
| Configuration | Included functions | Best fit |
|---|---|---|
| Basic | Inlet air filter; outlet air filter with check valve; feed/harvest and sampling lines; silicone and thermoplastic elastomer tubing; configurable end fittings | Routine seed, batch and fed-batch culture |
| Sensor-ready | Basic functions plus optical pH and dissolved-oxygen sensor spots and additional liquid lines | Monitored development, seed and production culture |
| Perfusion-ready | Sensor-ready functions plus an internal 5 µm retention membrane and dedicated perfusion connections | High-density culture, N-1 intensification and perfusion |
Confirm platform tray size, working-volume range, culture mode, gas and exhaust requirements, liquid lines, optical sensor compatibility and the intended controller before technical review.